在永远为白雪覆盖的科罗拉多小镇,生活着一群想法独特、行事怪异的小孩。经常充当四人组领导者的斯坦(特瑞·帕克 Trey Parker 配音)对流行元素永远抱怀疑态度,而面对喜欢的女孩又会忍不住呕吐;戴着绿色帽子的犹太小孩凯尔(麦特·斯通 Matt Stone 配音)因种族的关系经常和抱有歧视且贪婪自大的超级毒舌小胖子艾瑞克(Trey Parker 配音)发生冲突;永远裹得严严实实说话含混不清的肯尼(Matt Stone 配音),很悲惨地每集都死于意外,而下一集又若无其事地复活。四个小家伙以及镇上各种思想扭曲的人物、时不时乱入的名人。组成了妙语连珠、恶搞不断的南方公园大世界
After having a fight with Danny, Sam utters the words "There are days I wish I never met you" as she leaves. This wish is granted by Deisree, and the next day, Sam discovers that Danny has no idea who she is! Unfortunately, since Sam prodded Danny into checking out the Fenton Portal, he doesn't have any powers. Now, Sam must convince Danny back into the portal for another "accident" so that he can become Danny Phantom!